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By W. R. Hess (auth.), Yechiel Becker (eds.)

ISBN-10: 1461294371

ISBN-13: 9781461294375

ISBN-10: 1461323436

ISBN-13: 9781461323433

African swine fever (ASF) is brought on by a pandemic that's labeled as a member of the Iridovirinae kin. The disorder within the warthog, the average host, in Africa was once defined in 1921 through R. E. Montgomery. The reservoir of the vi rus is inti cks. The i ntroduct i on of household pi gs into territory occupied by way of warthogs i nf ected wi th ASF within the 1960's has endangered the pig world wide. The family pig is very delicate to ASF and develops a devastating illness that kills the pig with no giving the immune process an opportunity to safeguard the animal opposed to the virus an infection. the power of ASF virus to contaminate and ruin cells of the reticuloendothelial method leaves a defenseless host that succumbs to infection that may be defined as an obtained immune deficiency di sease of household pi gs. creation of the virus into Iberia within the 1960's ended in a sequence of ASF epidemics in Spain and Portugal . . and later in France, that prompted heavy financial losses. among 1976 and 1960, ASF virus made its visual appeal in Malta and Sardinia . . in addition to in Brazil, The Dominican Republic . . Haiti, and later in Cuba. In 1985-6 . . ASF seemed in Belgium and The Netherlands.

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ASF virus. 10). apparently has a predilection for the red pulp. marginal zones of the periarterial lymphoid sheaths. and periarterial macrophage sheaths of the spleen; the paracortical areas. interfollicular areas and post capillary venules of the lymph nodes; and Kupffer cells of the liver. Immunologists report localization of ingested foreign material and antigen in the periarterial macrophage sheaths. red pulp. and marginal zones of the periarterial lymphoid sheaths in the spleen. and medullary areas and follicular marginal zones of the lymph nodes (11).

TAXONOMY Although the morphology (17), the lack of structural glycoproteins (15), the absence of neutralizing antibodies and the requirement of the cell nucleus for virus DNA replication (33) are properties that ASF virus and frog virus (29) have in common, many other properties of ASF virus are similar to those of poxviruses. The DNA from both ASF and vaccinia virus is a unique sequence with hairpin loops and terminal inverted repeats (39-42). In contrast, iridovirus DNA is circularly permuted and has direct terminal repeats (43-45).

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African Swine Fever by W. R. Hess (auth.), Yechiel Becker (eds.)

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