E.E Payne's An Atlas of Pathology of the Brain PDF

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By E.E Payne

ISBN-10: 0718610091

ISBN-13: 9780718610098

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Brain 128:126–137. The Parkinson Study Group. 2004. Levodopa and the progression of Parkinson’s disease. N Engl J Med 351:2498–2508. , A. Antonini, T. Bovi, I. Pasquin, M. Steinmayr, G. Moretto, A. Fiaschi, and S. Ottaviani. 2009. Clinical and [123I]FP-CIT SPET imaging follow-up in patients with drug-induced parkinsonism. J Neurol 256:910–915. , P. Bergmans, J. Booij, A. Winogrodzka, E. A. van Royen, J. C. Stoof et al. 1998. Drug-naïve patients with Parkinson’s disease in Hoehn and Yahr stages I and II show a bilateral decrease in striatal dopamine transporters as revealed by [123I]beta-CIT SPECT.

C. Wolters et al. 1998. Imaging of dopamine transporters with iodine-123-FP-CIT SPECT in healthy controls and patients with Parkinson’s disease. J Nucl Med 39:1879–1884. , J. D. Speelman, H. W. Horstink, and E. C. Wolters. 2001. The clinical benefit of imaging striatal dopamine transporters with [123 I] FP-CIT SPECT in differentiating patients with presynaptic parkinsonism from those with other forms of parkinsonism. Eur J Nucl Med 28:266–272. Catafau, A. , and E. Tolosa. 2004. Impact of dopamine transporter SPECT using 123I-Ioflupane on diagnosis and management of patients with clinically uncertain Parkinsonian syndromes.

Other authors reported reduced striatal DAT binding in vascular parkinsonism, with values ranging in between levels of normal and cases with PD (Tzen et al. 2001). Similarly, in 20 patients with parkinsonism with cerebrovascular disease and without pre-existing PD (Lorberboym et al. 2004), striatal DAT binding was diminished in more than half (Zijlmans et al. 2007). Variable striatal DAT availability ranging from normal to pathological values in VP and overlapping in part with those observed in PD makes it difficult to separate those two entities even with the use of in vivo striatal DAT markers.

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An Atlas of Pathology of the Brain by E.E Payne

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